Global PS Product Development History

Time

Country

Product Status

1st generation products

Source: Bovine brain

1988

Italy

OTC drugs for Alzheimer's treatment

1990

United States

The treatment effect is confirmed

1992

Europe

The first generation PS is prohibited from selling due to the outbreak of mad cow disease

2nd generation products

Source: soybean

In the 1990s

Israel

Use phospholipase D to produce PS from soybean by biotransformation, replacing the first generation product

3rd generation products

Source: Marine life

2009

Israel

10% of deep-sea fish sources ω3-PS

2010

American

10% DHA PS of deep-sea fish liver

2016

China

30% of Norwegian herring seeds ω3-PS